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PhD Student

Naam bedrijf: 
Maastricht University

The Department of Complex Tissue Regeneration (CTR) is looking for a Ph.D. student to join a team designing dynamic materials for additive manufacturing and regenerative medicine. We have received recent funding to create novel materials to advance the fabrication of adaptable tissue constructs towards soft organ regeneration, and to unravel cell-material interactions with such dynamic soft matter.

Current biomaterials are typically static, while the biomaterials in the human body are inherently dynamic. This position will directly tackle this discrepancy by designing time- and mechanically-dependent properties into biocompatible hydrogels for 3D printing. The candidate will engage in the design, synthesis, characterization, and testing of new and existing biocompatible hydrogels designed for 3D printing of encapsulated cells. These hydrogels will be based on self-healing, shear-thinning, and reversible supramolecular interactions or dynamic covalent chemistry – exciting new areas of responsive biomaterials.

A successful candidate will join the biofabrication laboratory under guidance of Dr. Matthew Baker and Prof. Dr. Lorenzo Moroni. This position is within the Department of Complex Tissue Regeneration (CTR) in the MERLN Institute for Technology-Inspired Regenerative Medicine (merln.maastrichtuniversity.nl). The MERLN Institute is newly opened at Maastricht University. We are a collaborative, international, and interdisciplinary group with diverse expertise, including biomaterials science, chemistry, tissue engineering, fabrication, and stem-cell biology. We share newly renovated laboratory facilities with modern equipment. We have a long history as leaders in the field of tissue engineering and are particularly well-known for our orientation towards translational research into the market and the clinics.

Responsibilities:

This position is envisioned to drive the design, synthesis, and materials characterization of new bio-compatible hydrogels with unique time-dependent mechanical properties. The characterization of the hydrogel dynamics on cell culture and tissue engineering will be initially explored by the applicant, and the project will be supplemented by a post-doctoral associate to further develop candidate materials for 3D printing and tissue engineering, with an eye towards vascularization.

This position will be an integral part of a multidisciplinary and multi-university collaboration to thoroughly explore the use of dynamic chemistry (supramolecular, dynamic covalent, shape changing) in fabrication technologies from automotive parts, to customized artificial organs. Collaboration and communication across non-traditional disciplines, as well as clear data presentation to collaborators is a crucial part of a successful collaboration.

Must Have Requirements:

Candidates should have a Master’s degree in chemistry, materials science, or closely related field, with an affinity for regenerative medicine. A background in organic/polymer synthesis and materials characterization is highly valued. Additional knowledge on biofabrication, biomaterials design, and cell culture is a plus, yet is not necessary. Candidates who have done a Bachelor’s degree in a country where it is the norm to directly enter a PhD afterwards (e.g. USA) are welcome to apply, but must demonstrate significant independent research experience.

We are looking for creative thinkers who are prepared to take on highly challenging aims. The project will be very collaborative and interdisciplinary, with a core competency of materials design. This position will best suit an ambitious candidate who likes a fast-paced environment. Excellent knowledge of scientific English for speaking, reading, and writing are required. Knowledge of Dutch is not required.

Please send your application here: https://goo.gl/jnuywj

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